Table 2.

Differentially Expressed Genes That Comprise Two of the Most Significantly Upregulated Canonical Pathways from Ingenuity Pathway Analysis

Gene name	Fold change	Adjusted p-value	IL-8	NF-κB
Platelet-derived growth factor C	1.66	0.008	X
NF-κB inhibitor epsilon	1.56	0.008		X
Integrin subunit alpha 2b	2.48	0.018		X
Integrin subunit beta 3	2.46	0.018	X
Integrin subunit beta 5	2.16	0.018	X	X
Epidermal growth factor	1.93	0.022	X
NF-κB subunit 2	1.34	0.027		X
Ras homolog family member C	1.41	0.049	X
Intercellular adhesion molecule 1	1.35	0.060	X
Insulin receptor substrate 1	1.68	0.063	X	X
Vascular endothelial growth factor A	1.33	0.081	X
Phosphoinositide-3-kinase regulatory subunit	1.66	0.092	X	X

IL-8, interleukin-8 signaling; NF-κB, nuclear factor kappa B activation.