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. 2019 Oct 21;16(12):1541–1548. doi: 10.7150/ijms.37427

Figure 3.

Figure 3

In vitro characterization of AuNPs-anti-miR221. (A) TEM images; (B) Absorption bands; (C) Zeta potential; (D) Dynamic light scattering measurements; (E) The viability of LO2 after treatment of AuNPs or AuNPs-anti-miR221; (F) Fluorescence and dark-field imaging showing the nuclear targeting by AuNPs-anti-miR221. Blue, red and yellow represent the nuclei stained by Hoechst 33342, Cy3 labeled anti-miR221 and dark-field of AuNPs. All experiments were repeated three times and values are presented as mean ± SD. Note: AuNPs-anti-221 and Cy3-anti-221-AuNPs abbreviations indicate AuNPs-anti-miR221 and Cy3 labeled AuNPs-anti-miR221 respectively.