Figure 2.

Relationship between baseline chloride and bicarbonate concentration, study groups, and 30-day in-hospital mortality. The mean and 95% confidence interval (denoted by gray shading) for the probability of 30-day in-hospital mortality is displayed for patients in the balanced crystalloids group (blue) and in the saline group (red) relative to (A) baseline plasma chloride concentration and (B) baseline bicarbonate concentration, with locally weighted scatterplot smoothing. Although 30-day in-hospital mortality overall was lower in the balanced crystalloids group than the saline group, neither baseline chloride nor baseline bicarbonate concentration modified the effect of study group on in-hospital mortality.