Table 2.

Characteristics of Patients with and without Acute Kidney Injury, by Reference Creatinine Estimate

Variable	MDRD			Trauma MDRD			Admission creatinine			First day nadir
	No AKI N=4,684, (59%)	AKI N=3,294 (41%)	p Value	No AKI N=1,916 (24%)	AKI N=6,062 (76%)	p Value	No AKI N=6,284 (79%)	AKI N=1,694 (21%)	p Value	No AKI N=3,624 (46%)	AKI N=4,379 (54%)	p Value
Age, y, median (IQR)	36 (24–54)	48 (31–64)	<0.001	32 (22–48)	44 (29–61)	0.001	40 (26–5)	44 (28–61)	<0.001	41 (26–58)	41 (27–58)	0.67
Male sex, %	79	63	<0.001	82	69	<0.001	72	72	1.0	72	73	0.40
ISS, median (IQR)	19 (12–29)	21 (13–29)	<0.001	19 (12–29)	20 (13–29)	0.002	20 (12–29)	22 (13–29)	0.001	19 (12–29)	21 (13–29)	<0.001
SBP, mmHg, median (IQR)	124 (105–142)	121 (98–141)	<0.001	125 (106–142)	122 (100–142)	<0.001	123 (102–142)	120 (98–141)	0.007	124 (104–143)	120 (100–140)	<0.001
Hospital-free days, median (IQR)	18 (7–24)	15 (0–22)	<0.001	18 (8–24)	16 (2–23)	<0.001	17 (6–24)	13 (0–22)	<0.001	17 (6–24)	16 (1–23)	<0.001
Mortality, %	8%	13%	<0.001	7%	11%	<0.001	9%	16%	<0.001	10%	11%	0.01

MDRD, Modified Diet of Renal Diseases; SBP, arrival systolic blood pressure; TMDRD, Trauma Modified Diet of Renal Diseases