Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 1;10(27):6848–6857. doi: 10.7150/jca.36614

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

cAMP can modulate DNA damage, DNA repair and cell apoptosis to affect cellular survival or prognosis of patients with lung cancer. It can regulate the sensitivity to radiotherapy and chemotherapy in lung cancer patients, through the modulation of these three popular effectors: Bcl-2, IAPs and XRCC1. Given that these modulation of the three elements, cAMP can play an important role in the control of DNA damage and cell apoptosis. And then have an effect on the drug-resistance in lung cancer patients.