Table 3.
Differentially expressed genes of the UPR pathway between E-cig aerosol-treated and untreated NHOKs based on DNA microarray analysis.
| Gene # | Protein name | Protein ID | Average fold change |
|---|---|---|---|
| HSPA5 | Immunoglobulin heavy-chain binding protein (a.k.a., glucose-regulated protein 78) | BIP (GRP78) | 1.68 |
| ERN1 | Inositol-requiring enzyme 1 (a.k.a., endoplasmic reticulum to nucleus signaling 1) | IRE1α | 1.97 |
| XBP1 | X‑box binding protein 1 | XBP1 | 2.52 |
| EIF2AK3 | PRKR-like ER kinase | PERK | 1.35 |
| ATF6 | Activating transcription factor 6α | ATF6α | 1.01 |
| ATF4 | Activating transcription factor 4 | ATF4 | 3.65 |
| DDIT3 | C/EBP homologous protein (a.k.a., DNA-damage-inducible transcript 3) | CHOP | 9.60 |