Table 1.
The association of pure GGO nodules with the clinicopathologic characteristics of 1422 patients with lung cancer and treated with surgery.
| Characteristic | Total, n=1422 | Non-pure GGO nodule, n=1383 | Pure GGO nodule, n=39 | p-value |
|---|---|---|---|---|
| Gender, n (%) | ||||
| Male | 999 (70.3) | 981 (70.9) | 18 (46.2) | 0.001 |
| Female | 423 (29.7) | 402 (29.1) | 21 (53.8) | |
| Age, years | ||||
| ≤60 | 767 (53.9) | 742 (53.7) | 25 (64.1) | 0.197 |
| >60 | 655 (46.1) | 641 (46.3) | 14 (35.9) | |
| Smoking history, n (%) | ||||
| Never | 518 (36.4) | 492 (33.5) | 26 (66.7) | <0.001 |
| Former | 178 (12.5) | 175 (12.6) | 3 (7.7) | |
| Current | 726 (51.0) | 716 (51.7) | 10 (25.6) | |
| Histology, n (%) | ||||
| Adenocarcinoma | 697 (49.0) | 663 (47.9) | 34 (87.1) | <0.001 |
| Squamous | 519 (36.5) | 519 (37.5) | 1(2.6) | |
| SCLC | 109 (7.7) | 109 (7.9) | 0 (0) | |
| Other | 97 (6.8) | 92 (6.7) | 4(10.3) | |
| Tumor size, n (%) | ||||
| ≤3cm | 663 (46.6) | 635 (45.9) | 34 (87.2) | <0.001 |
| >3cm | 759 (53.3) | 748 (54.1) | 5 (12.8) | |
| Lymph node metastasis, n (%) | ||||
| No | 771 (54.2) | 734(53.1) | 37 (94.9) | <0.001 |
| Yes | 651 (45.8) | 649(46.9) | 2 (5.1) | |
| Pathological grade, n (%) | ||||
| Well | 169 (11.9) | 143 (10.3) | 26 (66.7) | <0.001 |
| Moderately | 645 (45.4) | 642 (46.4) | 3 (7.7) | |
| Poorly | 493 (34.6) | 491 (35.6) | 2 (5.1) | |
| Unknown | 115 (8.1) | 107 (7.7) | 8 (20.5) | |
| Pathological stage, n (%) | ||||
| I | 566 (39.8) | 533 (38.5) | 33 (84.6) | <0.001 |
| II | 392 (27.6) | 388 (28.1) | 4 (10.3) | |
| III | 464 (32.6) | 462 (33.4) | 2 (5.1) | |
SD standard deviation; SCLC small cell lung cancer; GGO ground glass opacity.