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. 2019 Oct 23;15(13):2774–2782. doi: 10.7150/ijbs.34888

Figure 2.

Figure 2

IH treatment enhanced aortic oxidative stress and HIF-1α expression. (A) Representative HIF-1α, VEGF, MMP2, MMP9 and the subunits of NAD (P) H gp-91 immunohistochemical staining images of aortas with indicated interventions. (B-C) Expression of HIF-1α, VEGF, MMP2, MMP9 and the subunits of NAD (P) H gp-91 in aortas with different interventions are shown. IH significantly exacerbated Ang II-induced aortic oxidative stress and MMPs expression as evaluated by western blotting. Mean± SEM, n=5 mice per each group (*p<0.05 vs. saline; #p<0.05 vs. Ang II, one-way ANOVA).