Table 1.
Parameters of glucose metabolism and correlations with the serum spexin level in the T2DM group and control group.
| T2DM | Control | P value | Correlation with the serum spexin level | ||
|---|---|---|---|---|---|
| r | P value | ||||
| Numbers | 23 | 22 | |||
| Age (years) | 55.3 ± 13.2 | 52.7 ± 17.4 | 0.725 | -0.011 | 0.941 |
| BMI (kg/m2) | 23.5 ± 2.8 | 22.3 ± 2.6 | 0.169 | -0.254 | 0.092 |
| FBG (mmol/L) | 9.2 ± 1.5 | 4.6 ± 0.5 | <0.001 | -0.583 | <0.001 |
| PBG1h (mmol/L) | 14.6 ± 3.4 | 7.2 ± 1.1 | <0.001 | -0.457 | 0.002 |
| PBG2h (mmol/L) | 15.3 ± 4.1 | 6.6 ± 1.1 | <0.001 | -0.502 | 0.001 |
| HbA1c (%) | 9.5 ± 2.1 | 5.6 ± 0.4 | <0.001 | -0.431 | 0.004 |
| FINS (μIU/mL) | 11.9 ± 3.4 | 10.3 ± 2.8 | 0.080 | -0.132 | 0.400 |
| PINS1h (μIU/mL) | 64.5 ± 22.6 | 63.8 ± 29.6 | 0.488 | 0.155 | 0.321 |
| PINS2h (μIU/mL) | 71.9 ± 25.3 | 45.9 ± 22.6 | 0.001 | -0.180 | 0.248 |
| TG (mmol/L) | 2.01±0.71 | 1.28±0.61 | 0.001 | -0.191 | 0.209 |
| TC (mmol/L) | 5.15±0.98 | 4.66±0.86 | 0.085 | -0.180 | 0.237 |
| LDL-C (mmol/L) | 3.57±0.96 | 2.73±0.78 | 0.002 | -0.270 | 0.072 |
| HDL-C (mmol/L) | 1.02±0.24 | 1.22±0.62 | 0.156 | 0.033 | 0.829 |
| Serum spexin (ng/mL) | 1.69 ± 1.07 | 3.82 ± 1.54 | <0.001 | ||
| HOMA-IR | 4.85 ± 1.68 | 2.12 ± 0.58 | <0.001 | -0.498 | 0.001 |
The data are presented as the means ± SD for continuous data. FINS, PINS1h and PINS2h were log-transformed before performing the correlation analysis.