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. 2019 Nov 8;15(13):2859–2871. doi: 10.7150/ijbs.39063

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Inhibition of M-CSF can aggravate the recruitment of macrophages to the triple-negative breast cancer (TNBC) cells. (A, B) Wound healing assay showed that the ability of scratch healing was significantly smaller after adding M-CSF antibody to the TNBC cell conditioned medium (CM) than that in which the M-CSF antibody was not added. P<0.05. (C, D) Adding M-CSF antibodies to CM led to a decrease in the cytoskeletal deformity of macrophages, while the content of F-actin was reduced. Scale bar, 10 µm.