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. 2019 Nov 8;15(13):2859–2871. doi: 10.7150/ijbs.39063

Figure 6.

Figure 6

M-CSF played a key role in macrophages recruitment and the infiltration of macrophages was higher in TNBC in vivo. (A) The detection of M-CSF and CD68 in paraffin-embedded breast cancer specimens. Brown staining denotes the immunoreactivity of M-CSF or CD68. The tumor sections were counterstained by Hematoxylin to label the nuclei. Scale bar, 50 µm. (B) Box plot analysis revealed higher CD68 and M-CSF immunohistochemistry (IHC) score in the xenograft TNBC tumor. ***P<0.0001. Bars represent the mean ± standard deviation (SD). (C) The detection of ER, M-CSF and CD68 in immunodeficient mice xenografts. Brown staining denotes the immunoreactivity of ER, M-CSF or CD68. Scale bar, 50 µm.