Table 2.
Description of the total number of compounds in the pathway.
| Pathway name | Total compounda | Hitsb | Raw pc | –Log (p) | Impactd |
|---|---|---|---|---|---|
| Arginine & proline metabolism | 77 | 8 | 2.57E-08 | 2.06E-06 | 0.356 |
| Aminoacyl-tRNA biosynthesis | 75 | 6 | 1.03E-05 | 0.00041 | 0.0563 |
| Glycine, serine & threonine metabolism | 48 | 5 | 1.80E-05 | 0.00048 | 0.137 |
| Pyridine metabolism | 60 | 4 | 0.00821 | 0.0164 | 0.0355 |
| Nitrogen metabolism | 39 | 3 | 0.00271 | 0.0372 | 0.000 |
| Glutamine & glutamate metabolism | 11 | 2 | 0.00279 | 0.0372 | 0.139 |
| Alanine, aspartate & glutamate metabolism | 24 | 2 | 0.0132 | 0.151 | 0.384 |
a
Total compound is the number of compounds involved in the pathway.
b
Hits is the matched number from the user uploaded data.
c
The raw p is the original p-value calculated from the enrichment analysis.
d
Impact value is calculated from pathway topology analysis for comparison among different pathways. It represents the cumulative percentage of importance for the matched metabolite nodes involved in a pathway. The importance of each metabolite node is calculated from centrality measures and represents the percentage with regard to the total pathway importance.