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Two-compartment pharmacokinetic analysis parameters
| Analyte | V1 (L/kg) | V2 (L/kg) | CL1 (L/kg/hr) | CL2 (L/kg/hr) |
|---|---|---|---|---|
| Allopregnanolone | 4.95 | 6.03 | 12.88 | 5.98 |
| Ganaxolone | 5.07 | 5.64 | 8.35 | 8.92 |
Parameters determined by two-compartment analysis with WinNonlin 7.0. V1, central volume of distribution; V2, peripheral volume of distribution; CL1, central compartment clearance; CL2, peripheral compartment clearance.
