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. 2019 Sep 17;75(1):117–125. doi: 10.1093/jac/dkz378

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© The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — DEA-C3D potassium salt causes a reduction in P. aeruginosa clinical CF isolate PA68 biofilms alone and in combination with tobramycin. (a) Total biofilm biomass, representing live and dead biomass combined. (b) Biofilm thickness distribution. (c) Total biofilm surface area coverage. Values for all parameters were obtained from COMSTAT analysis of CLSM images. Scatter plots show all data points from n=4, with the mean and SD. One-way ANOVA with Tukey’s multiple comparisons tests were used for statistical analyses. TOB, tobramycin.