TABLE 3—
Mean (95%CI) Differences in FEV1% Predicted at Baseline and Change in FEV1 Predicted Over Time as a Function of Baseline PG1
| FEV1% predicted at baseline and as a function of PG1 and time | |||||
|---|---|---|---|---|---|
| Male | Female | ||||
| Model | FEV1% predicted | Mean (95%CI) | P-value | Mean (95%CI) | P-value |
| Model allowing FEV1% predicted to differ by constant across all times based on baseline PG1 | |||||
| Unadjusted | Baseline PG1 < 160 | 98 (92, 104) | NA | 102 (95, 108) | NA |
| Baseline PG1 > 160 | 96 (88, 104) | NS2 | 86 (78, 95) | 0.0042 | |
| Change (per year) | 0.8 (0.1, 1.5) | 0.033 | 0.3 (−0.6, 1.3) | NS3 | |
| Adjusted1 | Baseline PG1 < 160 | 93 (78, 107) | NA | 113 (95, 131) | NA |
| Baseline PG1 > 160 | 92 (74, 110) | NS2 | 106 (85, 127) | 0.202 | |
| Change (per year) | 0.6 (0.5, 1.9) | 0.0013 | 0.3 (−0.3, 1.5) | 0.203 | |
| Model allowing FEV1% predicted to differ over time as function of PG14 | |||||
| Adjusted1 | Baseline PG1 < 160 | 92 (78, 106) | NA | 113 (91, 131) | NA |
| Baseline PG1 > 160 | 94 (76, 112) | NS2 | 106 (84, 127) | 0.162 | |
| Changer for baseline < 160 | 1.5 (0.6, 2.3) | 0.0013 | 0.7 (−1.2, 2.6) | NS3 | |
| Change for baseline >160 | 0.6 (−0.8, 1.9) | 0.203 | 1.1 (−0.5, 2.7) | NS3 | |
1
Adjusted for BMI percentile and age at study entry.
2
For the test of whether mean FEV1% predicted at baseline differed as a function of PG1.
3
For the test of whether the rate of change in FEV1% predicted changes over time.
4
Model includes interaction term for PG1 × time in study.