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. Author manuscript; available in PMC: 2020 Jan 26.
Published in final edited form as: Sci Immunol. 2019 Jul 26;4(37):eaaw6693. doi: 10.1126/sciimmunol.aaw6693

Figure 1: Alveolar macrophages provide a replication niche for M.tb. through the first 10 days of infection.

Figure 1:

(A) % of total mEmerald+ cells, (B) % mEmerald+ for each cell population, and (C) total number of mEmerald+ cells in the lung between 2 hours and 14 days after high dose aerosol infection with mEmerald-tagged H37Rv (n = 3 mice/time point). (D) Microscopy of BAL samples 1 and 10 days after high dose aerosol infection with mEmerald-tagged H37Rv and quantitation of bacteria per AM (n = 3 replicates/time point, each replicate was pooled from 3 mice). Abbreviations: AM = alveolar macrophages, PMN = neutrophils, Eosin = eosinophils, MDM = myeloid-derived macrophages, DC = dendritic cells. Data are presented as mean ± SEM. Data is representative of 2 independent experiments.