FIGURE 4.

PSMA-RADS-2: likely benign skeletal finding with uptake in patient with biochemically recurrent PCa. Patient was an avid bicyclist and had experienced several episodes of minor trauma over the years, including a recent back injury. Coronal CT (A), coronal ¹⁸F-DCFPyL PET (B), and coronal ¹⁸F-DCFPyL PET/CT images (C) show slightly depressed L1 superior endplate with smooth, linear uptake (arrows). This uptake can occur in healing fractures and generally does not indicate disease. We categorized this patient as PSMA-RADS-2 instead of PSMA-RADS-1B because in rare circumstances uptake in such a location may obscure uptake from PCa.