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In vivo demonstration of receptor-mediated binding by tilmanocept. Kidneys, liver, and urine were harvested 40 min after injection of a low scaled molar dose of 68Ga-labeled IRDye800-tilmanocept (FL-tilmanocept) or 68Ga-labeled DTPA-IRDye800-galactosyl-dextran (FL-gal-dextran); injection of a high scaled dose of FL-tilmanocept; or coinjection of FL-tilmanocept and 5.0 nmol/g tilmanocept.
