Table 2. Sequences and G-scores of 2 x 4 and 3 x 4 G-quadruplex regions located on the ribosomal surface of the Homo sapiens 28S rRNA (LSU).

Number	Region	LSU rRNA Sequence (5’ to 3’)	Highest G-score
1	ES7-a	GGCGGCGGGUCCGGCCGUGUCGGCGGCCCGGCGG	20
2	ES7-a	GGGGGCGGGCUCCGGCGGGUGCGGGGGUGGGCGGGCGGGGCCGGGGGUGGGGUCGGCGGGGG	60
3	ES7-b	GGCGGGGAAGGUGGCUCGGGGGG	19
4†	ES7-b	GGGAGGGCGCGCGGGUCGGGGCGGCGGCGGCGGCGGCGGUGGCGGCGGCGGCGGCGGCGGCGGG	38
5	ES7-g	GGGCCCGGGGGAGGUUCUCUCGGGG	19
6	ES12	GGCUCGCUGGCGUGGAGCCGGGCGUGG	20
7	ES15	GGACGGGAGCGGCGGGGGCGG	21
8	ES15	GGAGGGCGGCGGCGGCGGCGGCGGCGGGGGUGUGGGG	21
9	H63	GGGCUGGGUCGGUCGGGCUGGGG	38
10†	ES27-a	GGGGGAGCGCCGCGUGGGGGCGGCGGCGGGGGGAGAAGGGUCGGGGCGGCAGGGGCCGGCGGC GGCCCGCCGCGGGGCCCCGGCGGCGGGGGCACGG	40
11	ES27-a	GGGGGGCCCGGGCACCCGGGGGGCCGGCGGCGGCGGCGACUCUGG	37
12*	ES27-b	GGCGGGCGUCGCGGCCGCCCCCGGGGAGCCCGGCGGGCGCCGG	20
13	ES27-b	GGGGGCGGGGAGCGGUCGGGCGGCGGCGGUCGGCGGGCGGCGGGGCGGGGCGG	21
14	ES27-b	GGCGCGCGGCGGCGGCGGCGGCAGGCGGCGGAGGGGCCGCGGGCCGG	21
15	ES30	GGGGCCCGGGGCGGGGUCCGCCGGCCCUGCGGGCCGCCGG	21
16	ES39	GGGACCGGGGUCCGGUGCGG	20
17	ES39	GGGAAACGGGGCGCGGCCGGAGAGGCGG	20

*This region contains a loop longer than 7 nucleotides

^† These regions meet both 3 x 4 and 2 x 4 criteria.