Table 2:
Analysis of serum IgG autoantibodies.
| BP180 IgG 1 | BP230 IgG 1 | |||
|---|---|---|---|---|
| Comparison2 | Mean Ratio 3 95% CI |
p-value | Mean Ratio 95% CI |
p-value |
| ND+BP vs. BP CON | 1.234 0.788-1.933 |
0.3536 | 1.493 0.823-2.708 |
0.1840 |
| PD+BP vs. BP CON | 1.029 0.626-2.337 |
0.5675 | 1.241 0.516-2.981 |
0.6257 |
| DEM+BP vs. BP CON | 1.020 0.541-1.922 |
0.9510 | 1.500 0.646-3.487 |
0.3408 |
| STR+ BP vs. BP CON | 1.560 0.756-3.217 |
0.2249 | 1.798 0.687-4.711 |
0.2284 |
| PD+BP vs. STR+BP | 0.775 0.316-1.092 |
0.5735 | 0.690 0.209-2.277 |
0.5373 |
| DEM+BP vs. STR+BP | 0.654 0.271-1.575 |
0.3387 | 0.834 0.259-2.688 |
0.7585 |
| PD+BP vs. DEM+BP | 1.186 0.519-2.711 |
0.6827 | 0.827 0.275-2.484 |
0.7314 |
1
IgG antibodies specific for BP180 and BP230 were measured by ELISA.
2
Subjects included BP controls (BP CON), and BP patients with preceding neurologic disease (ND); Parkinson’s disease (PD+BP), dementia (DEM+BP), stroke (STR+BP)
3
Mean ratio, 95% confidence interval (CI), and p-value are indicated for each comparison. A p-value <0.0071 was considered significant.