Table 3:
Analysis of serum IgE antibodies.
| BP180 IgE2 | BP230 IgE2 | Total IgE3 | ||||
|---|---|---|---|---|---|---|
| Comparison1 | Mean Ratiod 95% CI |
p-value | Mean Ratio 95% CI |
p-value | Mean Ratio 95% CI |
p-value |
| ND+BP vs. BP CON | 0.760 0.504-1.139 |
0.1801 | 1.195 0.934-1.530 |
0.1540 | 0.889 0.443-1.787 |
0.7383 |
| PD+BP vs. BP CON | 0.581 0.325-1.038 |
0.0661 | 0.944 0.665-1.340 |
0.7429 | 0.290 0.107-0.787 |
0.0159 |
| DEM+BP vs. BP CON | 1.135 0.617-2.089 |
0.6789 | 1.084 0.774-1.519 |
0.6331 | 0.778 0.297-2.035 |
0.6040 |
| STR+ BP vs. BP CON | 0.586 0.318-1.077 |
0.0804 | 1.663 1.132-2.443 |
0.0100 | 1.792 0.598-5.372 |
0.2933 |
| PD+BP vs. STR+BP | 0.992 0.458-2.150 |
0.9844 | 0.568 0.353-0.914 |
0.0205 | 0.162 0.041-0.631 |
0.0094 |
| DEM+BP vs. STR+BP | 1.939 0.875-4.296 |
0.1013 | 0.652 0.409-1.040 |
0.0720 | 0.434 0.114-1.648 |
0.2164 |
| PD+BP vs. DEM+BP | 0.512 0.236-1.109 |
0.0884 | 0.870 0.561-1.350 |
0.5299 | 0.372 0.106-1.306 |
0.1209 |
1
Subjects included BP controls (BP CON), and BP patients with preceding neurologic disease (ND); Parkinson’s disease (PD+BP), dementia (DEM+BP), stroke (STR+BP)
2
IgE autoantibodies specific for BP180 and BP230 were measured by ELISA.
3
Total IgE was measured electrochemiluminescence.
4
Mean ratio, 95% confidence interval (CI), and p-value are indicated for each comparison. A p-value <0.0071 was considered significant.