Table 6.
Overall | Healthy Control | Nonfebrile DENV | OFI | Apparent DENV | |||||
---|---|---|---|---|---|---|---|---|---|
Fever−/DENV− | Fever−/DENV+ | Fever+/DENV− | Fever+/DENV+ | ||||||
Exposure Variables | n = 141 | n = 57 | n = 18 | n = 14 | n = 53 | ||||
Wald χ 2 | P Valuea | OR (95% CI) | P Valueb | OR (95% CI) | P Valueb | OR (95% CI) | P Valueb | ||
Ferritin (ng/mL)c | 12.51 | .006 | Reference | 1.40 (.75–2.62) | .3 | 1.72 (0.83–3.57) | .14 | 2.66 (1.53–4.62) | .0006 |
RBP (µmol/L)c | 13.04 | .005 | Reference | 2.74 (.49–15.40) | .25 | 0.02 (0.00–0.24) | .003 | 0.03 (.00–.30) | .003 |
AGP (g/L)d | 26.00 | <.0001 | Reference | 0.99 (.79–1.24) | .92 | 1.95 (1.44–2.65) | <.0001 | 1.81 (1.42–2.30) | <.0001 |
Abbreviations: AGP, alpha-1 acid glycoprotein; CI, confidence interval; DENV, dengue virus; OFI, other febrile illness; OR, odds ratio; RBP, retinol-binding protein.
a P values obtained using a Wald χ 2 tests for independence.
b P values obtained from polytomous logistic regression, Type 3 analysis of effects. Each illness category compared to“healthy control” as the reference group. Model is adjusted for age, sex, and body mass index.
cAdjusted for acute-phase response using the Thurnham correction factor.
dAGP modeled as value per 0.1 g/L.