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. 2019 Dec 13;6:319. doi: 10.1038/s41597-019-0317-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — The relationship between the funding, research, curation, and sharing steps of the NF-OSI. CTF and NTAP fund researchers, who in turn generate datasets, tools, and publications. Data are uploaded to Synapse, where the projects are curated, standard metadata is applied to the files, and publications are tracked. After these steps, these projects are connected to the NF Data Portal to facilitate exploration of study files, datasets, tools, and publications. When the nature of the data permit (i.e. the data are public, non-sensitive, and of a format that is compatible with sequence/array-focused archives) the data are also deposited in public archives such as the Sequence Read Archive (SRA)¹ or the Gene Expression Omnibus (GEO)².