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. 2019 Dec 13;10:5712. doi: 10.1038/s41467-019-13392-y

Fig. 1. Recurrence and co-association of U2AF1 S34F mutations.

Fig. 1

a Recurrence of U2AF1 S34F mutations in multiple data sets including data summarized from cBioPortal, TRACERx, Stanford patients, and cancer cell lines including LUAD. b The approximate phylogeny tree of the two samples collected from a Stanford LUAD patient, illustrating U2AF1 S34F mutation and CD74-ROS1 fusion as truncal events. c Co-occurrence of SLC34A2-ROS1 fusions and U2AF1 S34F mutations in LUAD subset of cohort in a: A total of 2112 cases were analyzed, with highlighted cases of S34F mutations and ROS1 fusions shown in red. A Fisher’s exact test was performed to determine statistical significance.