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. 2019 Dec 13;9:19102. doi: 10.1038/s41598-019-55617-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Binding of HIPP1 and insulator proteins to SBS-Cs and CP190-dCTCFs in pupae from lines bearing mod(mdg4)^u1 and Hipp^Δ1 mutations. (a) HIPP1 binding; (b) Su(Hw) and dCTCF binding; (c) CP190 binding. Designations of the analyzed lines are as described in Fig. 4. ChIP was performed with antibodies against HIPP1, the Su(Hw) N-terminal domain, CP190, and dCTCF. Statistical analysis was performed relative to the wild type condition. Other designations are as described in Fig. 2.