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. 2019 Dec 13;10:5703. doi: 10.1038/s41467-019-13686-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Three views of the fold-switched CI2_eng structure fitted to the electron density corresponding to one monomer in the cryo-EM 3D reconstruction. b Top and side views of the atomic-resolution structural model of the double-ring assembly of fold-switched CI2_eng monomers (purple and yellow) fitted into the cryo-EM volume (gray density). c Hydrophobic interface and salt-bridge network between adjacent fold-switched monomers within each ring of the toroidal assembly.