Table 1.
Study of cytokine profiles among different studied groups in MLNs and PPs cell culture supernatants by ELISA.
| Group | MLN | ANOVA | PP | ANOVA | ||
|---|---|---|---|---|---|---|
| Mean ± SD | F | p-value | Mean ± SD | F | p-value | |
| IL-10 (pg/ml) | ||||||
| Control | 35.2 ± 3.2 | 110.58 | 0.001 | 44.9 ± 3.8 | 103.4 | 0.000 |
| DSS | 31.3 ± 5.6 | 50.2 ± 2.4 | ||||
| S. obvelata | 55.2 ± 2.2 | 85.5 ± 5.3 | ||||
| S.obvelata + DSS | 77.4 ± 5.4 | 113.3 ± 9.4 | ||||
| DSS + S. obvelata | 64.5 ± 3.3 | 95.6 ± 8.5 | ||||
| TNF-α (pg/ml) | ||||||
| Control | 60.1 ± 3.3 | 92.12 | 0.001 | 40.5 ± 3.5 | 79.6 | 0.001 |
| DSS | 141.3 ± 7.3 | 97 ± 7.9 | ||||
| S. obvelata | 71.2 ± 5.8 | 48.2 ± 4.7 | ||||
| S.obvelata + DSS | 92.4 ± 9.7 | 59.3 ± 4.7 | ||||
| DSS + S. obvelata | 119.9 ± 10.8 | 74.9 ± 6.3 | ||||
| IFN-γ (pg/ml) | ||||||
| Control | 22.3 ± 2.3 | 102.89 | 0 001 | 16.2 ± 0.3 | 116.5 | 0.001 |
| DSS | 104.5 ± 9.8 | 78.9 ± 3.9 | ||||
| S. obvelata | 44.8 ± 4.8 | 38.9 ± 5.3 | ||||
| S.obvelata + DSS | 63.5 ± 7.4 | 43.6 ± 4.6 | ||||
| DSS + S. obvelata | 86.1 ± 8.9 | 61.1 ± 7.4 | ||||
| IL-17 (pg/ml) | ||||||
| Control | 41.1 ± 1.8 | 118.6 | 0.001 | 21.9 ± 2.8 | 111.8 | 0.001 |
| DSS | 109.8 ± 10.7 | 82.1 ± 6.3 | ||||
| S. obvelata | 52.9 ± 3.8 | 41.2 ± 2.5 | ||||
| S.obvelata + DSS | 64 ± 3.5 | 50.6 ± 5.2 | ||||
| DSS + S. obvelata | 82.1 ± 2.8 | 52.8 ± 5.18 | ||||