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. 2019 Dec 13;10:5699. doi: 10.1038/s41467-019-13575-7

Fig. 5. Cortical and sub-cortical details of the SIGMA anatomical atlas.

Fig. 5

a, b Lateral and dorsal views of the cortical areas after normalization of the Tohoku atlas to the SIGMA anatomical template. The cortex has been segmented into cortical areas such as auditory (A), insular (In), temporal (T), limbic (L), olfactory (O), somatosensory (S), motor (M), cingulate (Cg), retrosplenial (Rs), parietal (P) and visual (V). Each area has been subdivided (using the Paxinos-Watson atlas) into functional areas (i.e. primary and secondary motor cortices) or structural areas (i.e. agranular, dysgranular, agranular/dysgranular, granular and posterior agranular insular cortices). c, d Lateral and dorsal views of sub-cortical structures (hippocampus and white matter tracts) after normalization of the Waxholm atlas on the SIGMA anatomical template. Legend of labeled regions:− Auditory: Au1 = primary auditory cortex; dAu2, vAu2 = secondary auditory cortex, dorsal and ventral areas. − Insular: AI, ADI = agranular insular and dysgranular insular cortices; GI, DI = granular and dysgranular insular cortices; AIP = posterior agralunar insular cortex. − Temporal: TeA = temporal association cortex; Ect = ectorhinal cortex. − Limbic: Fr = frontal association cortex; DLO = dorsolateral orbital cortex; OFr = orbitofrontal region; PrL = prelimbic cortex. − Olfactory: Prh = perirhinal cortex; Prh-35, Prh-36 = perirhinal areas 35 and 36; Ent = entorhinal cortex; L-Ent, M-Ent = lateral and medial entorhinal cortices; L-Ent-Int, L-Ent-Ext = lateral entorhinal cortex, internal and external parts. − Somatosensory: S1J, S1FL, S1HL, S1SH, S1ULp, S1Tk, S1BF = primary somatosensory cortex, jaw, forelimb, hindlimb, shoulder, upper lip, trunk and barrel field regions; S1DZ, S1DZ0 = primary somatosensory cortex, dysgranular region and dysgranular zone 0; S2 = secondary somatosensory cortex. − Motor: M1, M2 = primary and secondary motor cortices. − Cingulate: Cg1, Cg2 = primary and secondary cingular cortices. − Retrosplenial: RGa, RGb = retrosplenial granular A and B cortices; RSD = retrosplenial dysgranular cortex. − Parietal: lPA, mPA = lateral and medial parietal associative cortices; pcP, pdP, prP = parietal cortex postero-caudal, dorsal and rostral parts. − Visual: V1 = primary visual cortex; V1b, V1M = primary visual cortex, binocular and monocular areas; V2L = secondary visual cortex, lateral area; V2ML, V2MM = secondary visual cortex, mediolateral and mediomedial areas. − Hippocampus: CA1, CA2, CA3 = cornu ammonis areas; DG = dentate gyrus. − White matter tracts: ac = anterior commissure; cc = corpus callosum; f = fornix; Hb = habenular commissure; ic = internal capsule; ml = medial lemniscus; opt = optic tract; pc = posterior commissure; sp5 = spinal trigeminal 5 tract; Th = thalamus.