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Effect of age of the mother at childbirth on (A) the divergence (in drift units) of heteroplasmies (for 118 and 124 mothers who gave birth at 15–30 and 30–46 y of age, respectively), and (B) the number of putative germline de novo mutations in her children (50 mutations overlapping between the OPL and the heuristic approaches were included, 249 mothers were analyzed).
