Table 2.
Model inputs
| Parameters | Base case value | Range tested (%) |
|---|---|---|
| Unit drug costs (RMB) | ||
| Unit cost of docetaxel (cost per mg) | 73.62 | ± 20 |
| Unit cost of abiraterone (cost per mg) | 0.58 | ± 20 |
| Unit cost of prednisolone/prednisone (cost per mg) | 1.33 | ± 20 |
| Dosage | ||
| Daily dosage of docetaxel (mg/m2) | 75 | ± 20 |
| Daily dosage of abiraterone (mg) | 1000 | ± 20 |
| Daily dosage of prednisolone (mg) | 5 | ± 20 |
| Average height (m) | 1.615 | ± 20 |
| Average weight (kg) | 61.8 | ± 20 |
| Other medical costs (RMB) | ||
| Hospitalisation costs for chemotherapy | 318 | ± 20 |
| Preventive drugs for chemotherapy | 620 | ± 20 |
| ADT cost per month | 2050 | ± 20 |
| Laboratory test costs | 500 | ± 20 |
| Inpatient OOP | 15 | ± 20 |
| Outpatient OOP % | 25% | ± 20 |
| Costs of adverse events (RMB) | ||
| Hypertension | 98.70 | ± 50 |
| Hypokalaemia | 65.00 | ± 50 |
| ALT increased | 225.68 | ± 50 |
| Hyperglycaemia | 115.00 | ± 50 |
| AST increased | 225.68 | ± 50 |
| Bone pain | 583.00 | ± 50 |
| Cardiac disorder | 1000.00 | ± 50 |
| Anaemia | 271.70 | ± 50 |
| Back pain | 73.60 | ± 50 |
| Spinal-cord compression | 1235.00 | ± 50 |
| Fatigue | 540.44 | ± 50 |
| Allergic reaction | 75.00 | ± 50 |
| Diarrhoea | 31.44 | ± 50 |
| Stomatitis | 74.00 | ± 50 |
| Neuropathy | 375.84 | ± 50 |
| Thromboembolism | 1794.20 | ± 50 |
| Sudden death | 3200.00 | ± 50 |
| Thrombocytopenia | 3518.04 | ± 50 |
| Neutropaenia | 720.80 | ± 50 |
| Febrile neutropaenia | 1787.20 | ± 50 |
| Infection with neutropaenia | 14,764.05 | ± 50 |