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. 2019 Dec 10;12:10787–10797. doi: 10.2147/OTT.S226044

Figure 3.

Figure 3

miR-204-5p inhibitor attenuated the effects of KCNQ1OT1 silencing on cell proliferation, apoptosis and autophagy in NSCLC. A549 and H460 cells were transfected with sh-KCNQ1OT1+anti-miR-204-5p, sh-KCNQ1OT1, sh-KCNQ1OT1+anti-miR-NC or sh-NC. (A) The expression of miR-204-5p in transfected A549 and H460 cells. (B, C) Cell viability of transfected A549 (B) and H460 cells (C). (D) Cell apoptosis of transfected A549 and H460 cells. (E, F) The expression of apoptosis-related protein cleaved caspase-3, cleaved caspase-9, Bax and anti-apoptosis protein BCL-2 in transfected A549 (E) and H460 cells (F). (G, H) Protein expression of autophagy markers LC3 and P62 in transfected A549 (G) and H460 cells (H). *P<0.05.