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. 2019 Dec 10;14:9777–9792. doi: 10.2147/IJN.S230269

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© 2019 Sadeghi et al.

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In vitro cytotoxicity studies using mouse fibroblast L929 cells. (A) lysostaphin in encapsulated and free forms and blank niosomes, (B) LL-37 in encapsulated and free forms and blank niosomes, (C) lysostaphin/LL-37 in encapsulated and free forms and blank niosomes. Values represent mean±SD, n=3. *P<0.05, **P<0.01, ***P< 0.001. The values written in the x-axis of part (C) are related to lysostaphin/LL-37 concentrations, respectively. No cytotoxicity was observed for lysostaphin/LL-37 in encapsulated and free forms at concentrations of MIC or higher than MIC.