Table 2.
Pharmacokinetic Parameters of Cur and Gal-BSA-Cur NPs
Parameter | Gal-BSA-Cur NPs | Cur |
---|---|---|
AUC (0–48 hrs)/(ng/mL*h). | 1047.6±41.2 | 775.4±35.7 |
MRT(0–48 hrs)/h | 22.6±0.4 | 21.7±0.8 |
Cmax(ng/mL) | 48.7±7.4 | 25.2±7.0 |
Tmax/h | 0.5 | 2 |
Abbreviations: Cur, curcumin; Gal-BSA-Cur NPs, curcumin-loaded galactosylated BSA nanoparticles; AUC, area under the curve; MRT, mean retention time; Cmax, peak plasma concentration; Tmax, time at peak concentration.