Figure 2. Size distribution of core-shell electrospun fibers with different PLA/PEG formulations over 40 days in phosphate buffered solution.
(A) SEM images of fibers (10% PLA + 0, 1, 10, or 100 mg/ml PEG) at day 0, 1, 7, 14, and 40 (Mag: 10,000x; scale bar: 5 μm). Insert: SEM images of each specimen (10% PLA + 0, 1, 10, or 100 mg/ml PEG) at day 7, 14, and 40 (Mag: 35x; scale bar: 500 μm) (B) Diameters of electrospun PLA nanofibers with different concentration of PEG cultivated in PBS over 40 days (electrospun fibers were examined by SEM and fiber size measured using ImageJ). Line= P < 0.05 between groups, *= P < 0.05 compared to 0 day, **= P < 0.05 compared to 0, and 1 day, #= P < 0.05 compared to 0, 1, and 7 day, ##= P < 0.05 compared to 0, 1, 7, and 14 day, += P < 0.05 compared to 0, and 7 day.