Table I:
Patient characteristics and prevalence rates for calcification and lipid pools.
| Total (n=65) | Unruptured (n=48) | Ruptured (n=17) | p value | |
|---|---|---|---|---|
| Patient Clinical Characteristics | ||||
| Age (years) | 57.50 (30 – 79) | 58 (30 – 79) | 54 (43 – 66) | 0.089 |
| Female Sex (%) | 50/65 (77) | 36/48 (75) | 14/17 (82) | 0.741 |
| Family History for IAs (%) | 15/65 (23) | 13/48 (27) | 2/17 (12) | 0.478 |
| Smoker (%) | 23/65 (35) | 17/48 (35) | 6/17 (35) | 1.000 |
| Hypertensive (%) | 28/65 (44) | 21/48 (44) | 7/17 (41) | 1.000 |
| Anti-thrombotic medication (%) | 14/65 (22) | 14/48 (29) | 0/17 (0) | 0.024* |
| Statins (%) | 16/65 (25) | 15/48 (31) | 1/17 (6) | 0.086 |
| Type II Diabetes | 6/65 (9) | 5/48 (10) | 1/17 (6) | 1.000 |
| Size [mm3] | 7.6 (4.6 – 15.6) | 7.6 (4.6 – 14.5) | 9.2 (4.8 – 15.6) | 0.642 |
| Aspect Ratio | 1.06 (0.4 – 3.6) | 1.05 (0.5 – 2.0) | 1.18 (0.4 – 3.6) | 0.509 |
| Blebs/Lobulations | 19/65 (29) | 13/48 (27) | 6/17 (35) | 0.298 |
| Location | ||||
| MCA | 37/65 (57) | 29/48 (60) | 8/17 (47) | 0.563 |
| ICA | 8/65 (12) | 7/48 (15) | 1/17 (6) | 0.667 |
| ACOM | 8/65 (12) | 6/48 (13) | 2/17 (12) | 1.000 |
| PCOM | 6/65 (9) | 3/48 (6) | 3/17 (18) | 0.159 |
| Others¥ | 5/65 (8) | 3/48 (6) | 2/17 (12) | 0.592 |
| Prevalence Rates of Calcification and Lipid Pools in IAs | ||||
| Calcification (%) | 51/65 (78) | 40/48 (83) | 11/17 (65) | 0.167 |
| Lipid pools (%) | 39/65 (60) | 29/48 (60) | 10/17 (59) | 0.783 |
| Both calcification and lipid pools (%) | 30/65 (46) | 25/48 (52) | 5/17 (29) | 0.158 |
| Wall Type I, II (“Non- atherosclerotic calcification”) | 39/65 (60) | 28/48 (58) | 11/17 (65) | 0.380 |
| Wall Type III (“Atherosclerotic calcification”) | 12/65 (18) | 12/48 (25) | 0/17 (0) | 0.027* |
Median and range are given for continuous variables.
*
P<0.5 (X2, Fisher’s Exact Test or Mann-Whitney U test).
¥
Other aneurysm locations in this study with a single case include ruptured aneurysms: BA tip, PICA; and unruptured aneurysms: ACA, PCOM-ICA, VA.
Abbreviations used: MCA = Middle Cerebral Artery, ICA = Internal Carotid Artery, ACOM = Anterior Communicating Artery, PCOM = Posterior Communicating Artery, BA = Basilar Artery, PICA = Posterior Inferior Cerebellar Artery, ACA = Anterior Cerebral Artery, VA = Vertebral Artery.