Table 2.
Weekly Plasma Protoporphyrin, μM on treatment with 100 mg/Kg INH
Week | *WT-1 | WT-2 | Median | Range | ||||
---|---|---|---|---|---|---|---|---|
0 | 0.038 | 0.024 | 0.031 | 0.014 | ||||
1 | 0.154 | 0.154 | ||||||
2 | 0.068 | 0.042 | 0.055 | 0.026 | ||||
3 | 0.020 | 0.016 | 0.018 | 0.004 | ||||
4 | 0.008 | 0.004 | 0.006 | 0.004 | ||||
Week | §KO-1 | KO-2 | KO-3 | KO-4 | KO-5 | |||
0 | 0.281 | 0.328 | 0.454 | 0.221 | 0.233 | 0.233 | ||
1 | 0.237 | 0.444 | 0.320 | 0.410 | 0.380 | 0.380 | 0.207 | |
2 | 0.177 | 0.197 | 0.290 | 0.252 | 0.504 | 0.252 | 0.327 | |
3 | 0.127 | 0.166 | 0.216 | 0.404 | 0.202 | 0.202 | 0.277 | |
4 | 0.076 | 0.051 | 0.035 | 0.028 | 0.046 | 0.046 | 0.048 |
WT-wild type,
KO- Irp2−/− mice.