Table 3.
Liver Protoporphyrin nmol/g tissue.
Mouse | 1 | 2 | 3 | 4 | 5 | Median | Range | ||
---|---|---|---|---|---|---|---|---|---|
Untreated | *WT | 0.141 | 0.219 | 0.180 | 0.097 | 0.205 | 0.160 | 0.122 | |
Untreated | §KO | 2.093 | 4.272 | 3.658 | 4.089 | 1.793 | 2.875 | 2.479 | |
‡Treated | *WT | 0.148 | 0.143 | 0.220 | 0.176 | 1.567 | 0.162 | 1.424 | |
Treated | §KO | 0.613 | 2.121 | 0.139 | 1.378 | 0.546 | 0.579 | 1.982 |
WT-wild type,
KO- Irp2−/− mice.
Treated mice received INH, 100 mg/Kg 5 of 7 days/week for 4 weeks.