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. 2019 Aug 13;7(6):379–395. doi: 10.1093/gastro/goz032

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© The Author(s) 2019. Published by Oxford University Press and Sixth Affiliated Hospital of Sun Yat-sen University

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 8. — Barrett’s esophagus with features suspicious for carcinoma. (A) This biopsy shows features of high-grade dysplasia (HGD). In addition, there are a few glands with eosinophilic luminal debris (H&E stain, magnification 100×). (B) This biopsy shows HGD. In addition, there is one single cell infiltrating into the lamina propria (H&E stain, magnification 100×). (C) This biopsy shows HGD. In addition, there are a few glands with eosinophilic luminal debris and incorporation of neoplastic glands onto the squamous epithelium (H&E stain, magnification 200×). (D) This biopsy shows HGD. In addition, there is back-to-back glandular crowding (H&E stain, magnification 100×). All these features are worrisome for, but not diagnostic of, intramucosal adenocarcinoma.