Table 1.
Information of AS events in each prognostic signature
| Type | ID | B | HR | Lower | Upper | P |
|---|---|---|---|---|---|---|
| AA | EFNA4_AA_7933 | −1.611 | 0.2 | 0.081 | 0.494 | <.001 |
| GTDC1_AA_55511 | 0.85 | 2.339 | 1.645 | 3.326 | <.001 | |
| POLD2_AA_79475 | 0.792 | 2.208 | 1.329 | 3.668 | .002 | |
| RELA_AA_16902 | −6.099 | 0.002 | 0 | 0.142 | .004 | |
| RPS6KA1_AA_1286 | −0.269 | 0.764 | 0.657 | 0.889 | <.001 | |
| AD | ANXA2_AD_30958 | 1.338 | 3.812 | 1.485 | 9.787 | .005 |
| CHTF18_AD_33022 | −0.094 | 0.911 | 0.869 | 0.954 | <.001 | |
| TF_AD_66850 | 2.019 | 7.528 | 2.336 | 24.26 | .001 | |
| ZBTB45_AD_52479 | 0.047 | 1.048 | 1.023 | 1.073 | <.001 | |
| ZNF302_AD_48995 | −0.065 | 0.937 | 0.902 | 0.974 | .001 | |
| AP | ADORA3_AP_4173 | 3.497 | 33.008 | 4.532 | 240.425 | .001 |
| AP1B1_AP_61602 | 3.132 | 22.93 | 2.467 | 213.151 | .006 | |
| HDAC9_AP_78886 | 0.019 | 1.019 | 1.007 | 1.032 | .002 | |
| KLK10_AP_51263 | 0.082 | 1.086 | 1.023 | 1.153 | .007 | |
| PPAPDC1A_AP_13280 | 0.085 | 1.089 | 1.02 | 1.162 | .011 | |
| AT | BTNL9_AT_75038 | −0.085 | 0.919 | 0.87 | 0.97 | .002 |
| COX6B2_AT_52075 | −0.279 | 0.757 | 0.663 | 0.864 | <.001 | |
| CSGALNACT2_AT_11317 | −0.241 | 0.786 | 0.674 | 0.917 | .002 | |
| DST_AT_76557 | −0.177 | 0.838 | 0.714 | 0.984 | 0.031 | |
| SYNE1_AT_78181 | −0.103 | 0.902 | 0.863 | 0.943 | <.001 | |
| ES | CCAR1_ES_11956 | 0.133 | 1.142 | 1.051 | 1.241 | .002 |
| PPP3CB_ES_12157 | 0.518 | 1.679 | 1.058 | 2.665 | .028 | |
| TRIT1_ES_1916 | −2.407 | 0.09 | 0.015 | 0.531 | .008 | |
| WWOX_ES_37677 | −2.111 | 0.121 | 0.056 | 0.263 | <.001 | |
| DMTF1_ES_80295 | −1.467 | 0.231 | 0.093 | 0.57 | .001 | |
| HAT1_ES_55964 | −0.265 | 0.768 | 0.659 | 0.894 | .001 | |
| PPA2_ES_70200 | 3.831 | 46.096 | 7.177 | 296.055 | <.001 | |
| ST13_ES_62398 | −3.728 | 0.024 | 0.004 | 0.134 | <.001 | |
| ME | C4orf29_ME_70560 | −0.05 | 0.951 | 0.91 | 0.994 | .025 |
| OPN3_ME_204971 | 0.151 | 1.163 | 1.023 | 1.322 | .021 | |
| RPE_ME_100824 | −0.02 | 0.98 | 0.967 | 0.993 | .002 | |
| SRPK1_ME_75933 | −0.289 | 0.749 | 0.582 | 0.964 | .025 | |
| TGFBI_ME_73474 | 19.844 | 4.15E + 08 | 1710.923 | 1.01E + 14 | .002 | |
| RI | ARMCX4_RI_89653 | −0.039 | 0.961 | 0.927 | 0.997 | .033 |
| HYAL1_RI_64995 | −0.149 | 0.861 | 0.795 | 0.933 | <.001 | |
| LUC7L_RI_32846 | −0.024 | 0.976 | 0.954 | 0.999 | .037 | |
| MS4A6A_RI_16057 | −0.08 | 0.923 | 0.862 | 0.988 | .021 | |
| RPL30_RI_84641 | 0.457 | 1.579 | 1.066 | 2.339 | .023 | |
| SLC45A4_RI_85333 | −0.058 | 0.943 | 0.919 | 0.968 | <.001 | |
| TMOD3_RI_30632 | −3.267 | 0.038 | 0.007 | 0.202 | <.001 | |
| UBAP2_RI_86134 | −7.086 | 0.001 | 0 | 0.035 | <.001 | |
| ALL | RRP12_ES_12699 | −0.6 | 0.549 | 0.433 | 0.695 | <.001 |
| ST13_ES_62398 | −2.793 | 0.061 | 0.008 | 0.444 | .006 | |
| UBAP2_RI_86134 | −5.526 | 0.004 | 0 | 0.071 | <.001 | |
| SYNE1_AT_78181 | −0.114 | 0.892 | 0.848 | 0.938 | <.001 | |
| HSD11B1L_ES_46873 | 0.041 | 1.041 | 1.018 | 1.066 | .001 | |
| TRIT1_ES_1916 | −3.337 | 0.036 | 0.009 | 0.143 | <.001 | |
| KLC1_AD_29492 | −0.786 | 0.456 | 0.302 | 0.687 | <.001 |
Abbreviations: AA, alternate acceptor site; AD, alternate donor site; AP, alternate promoter; AT, alternate terminator; ES, exon skip; ME, mutually exclusive exons; RI, retained intron, HR, hazard ratio.