Table 3.
Univariable and multivariable analysis of overall survival (OS)
| Characteristic | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P‐value* | HR (95% CI) | P‐value* | |
| Age ≥ 50 y | 1.26 (1.18‐1.33) | <.001 | 1.28 (1.20‐1.36) | <.001 |
| Race | ||||
| White | 1 (reference) | 1 (reference) | ||
| Black | 1.25 (1.17‐1.33) | <.001 | 1.03 (0.97‐1.10) | .311 |
| Other | 0.79 (0.71‐0.88) | <.001 | 0.75 (0.67‐0.84) | <.001 |
| Unknown | 0.25 (0.12‐0.53) | <.001 | 0.22 (0.11‐0.47) | <.001 |
| Marital status | ||||
| Married | 1 (reference) | 1 (reference) | ||
| Unmarried | 1.66 (1.57‐1.79) | <.001 | 1.28 (1.21‐1.35) | <.001 |
| Unknown | 1.33 (1.19‐1.50) | <.001 | 1.16(1.04‐1.31) | .012 |
| Tumor grade | ||||
| I/II | 1 (reference) | 1 (reference) | ||
| III/IV | 1.27 (1.18‐1.36) | <.001 | 1.15 (1.07‐1.24) | <.001 |
| Unknown | 1.77 (1.53‐2.05) | <.001 | 1.06 (0.87‐1.17) | .937 |
| T stage | ||||
| T1 | 1 (reference) | 1 (reference) | ||
| T2 | 2.24 (2.09‐2.40) | <.001 | 1.93 (1.79‐2.07) | <.001 |
| T3 | 4.92 (4.52‐5.36) | <.001 | 2.92 (2.65‐3.20) | <.001 |
| T4 | 10.66 (9.82‐11.57) | <.001 | 3.67 (3.33‐4.05) | <.001 |
| N stage | ||||
| N0 | 1 (reference) | 1 (reference) | ||
| N1 | 2.70 (2.54‐2.87) | <.001 | 1.99 (1.86‐2.12) | <.001 |
| N2 | 4.22 (3.88‐4.59) | <.001 | 2.92 (2.67‐3.19) | <.001 |
| N3 | 7.41 (6.83‐8.03) | <.001 | 3.28 (2.99‐3.61) | <.001 |
| Metastasis | 12.02 (11.25‐12.84) | <.001 | 3.74 (3.45‐4.06) | <.001 |
| AC Histology | 0.58 (0.43‐0.78) | <.001 | 0.61 (0.45‐0.83) | .002 |
| Radiation therapy | 0.63 (0.60‐0.66) | <.001 | 0.80 (0.76‐0.85) | <.001 |
| Chemotherapy | 0.65 (0.62‐0.69) | <.001 | 0.45 (0.42‐0.47) | <.001 |
| Surgery | 0.16 (0.15‐0.17) | <.001 | 0.44 (0.41‐0.48) | <.001 |
Abbreviations: AC, apocrine carcinoma; CI, confidential interval; HR, hazard ratios; SHR, subdistribution hazard ratio.
*
P values from the Cox proportional hazard regression model.