TABLE 2.

Genes repressed during the recovery phase of HHP-injured B. subtilis

Gene	Gene product (function)	Expression ratioa
		2 h/0 h	4 h/0 h	4 h/2 h
ahpC	Alkyl hydroperoxide reductase (small subunit)	−3.94
ahpF	Alkyl hydroperoxide reductase (large subunit)	−3.64
bfmBAA (bkdA1)	Branched-chain alpha-keto acid dehydrogenase E1 subunit	−2.58
csbDb	General stress protein	−3.39
gapB	Glyceraldehyde-3-phosphate dehydrogenase	−2.47
hag	Flagellin protein	−4.46
mntA	Manganese ABC transporter (membrane protein)	−2.89
mntB	Manganese ABC transporter (ATP-binding protein)	−3.33
pckA	Phosphoenolpyruvate carboxykinase	−2.92
rbsA	Ribose ABC transporter (ATP-binding protein)	−3.16
spoVG	Stage V sporulation protein G (spore cortex synthesis)	−3.32
yflTb	General stress protein	−3.16
yqgZ (mgsR)	Spx paralog controls a subregulon within general stress response	−3.71
ytxH	General stress protein	−2.55
hpf (yvyD)	Dimerization of 70S ribosome	−4.45
ywsB	Unknown; putative cell wall binding protein	−3.27
citZ	Citrate synthase II	−2.69	−2.14
gsiB	General stress protein	−2.73	−1.74
katA	Vegetative catalase 1	−4.06	−3.52
mntC	Manganese ABC transporter (membrane protein)	−3.40	−1.94
mrgA	Metalloregulation DNA-binding stress protein; E. coli Dps homolog	−3.34	−3.02
srfAA	Surfactin synthetase	−2.45	−2.60
ybyB	Unknown	−4.72	−3.16
yhzC	General stress protein	−2.86	−2.55
ykzI	General stress protein	−3.94	−3.57
appC	Oligopeptide ABC transporter (permease)	−1.97	−3.91	−1.94
phrA	Phosphatase RapA inhibitor	−1.84	−3.76	−1.92
rapA	Response regulator aspartate phosphatase	−2.08	−3.75	−1.67
ybcO (skfA)	Sporulation killing factor	−2.22	−3.62	−1.40
yydF	Inducer of LiaRS	−2.65	−3.83	−1.19
mntD	Manganese ABC transporter		−2.76
nhaX	Regulator of nhaC		−2.67
srfAB	Surfactin synthetase		−2.59
clpE	Clp ATPase			−3.45
pstA	Phosphate ABC transporter (permease)			−3.09
mtlD	Mannitol-1-phosphate 5-dehydrogenase			−3.40
citB	Aconitase			−3.26
tuaG	Biosynthesis of teichuronic acid			−2.39

^aExpression ratio indicates the average value of the log₂ ratio between two independent microarray results.

^bNot reproducible by RT-qPCR analysis.