Figure 2.

Circular bar plot describing the studies performed using medications that modify anatomic traits in OSA patients. Only observational studies and clinical trials in which the apnea-hypopnea index (AHI) or the respiratory disturbance index (RDI) was reported were considered. No case reports or case series were included. AHI reduction refers to percent change from placebo values (or baseline when placebo was not available). Data represents a weighted average of AHI reductions if more than one study was testing the same medication(s). Study length (see legend) refers to the longest study performed using a particular medication. Every asterisk represents one single significant study. See text for specific differences and details of the studies considered. HT: hypertension.