Figure 5.

Prognostic value of CTCcl-associated gene signature in patients with basal-like breast cancer (BC), most of whom have TNBC. Fifty-four genes were found to be upregulated in TNBC PDX models with CTCcls. Gene-expression profiles of 360 basal-like BC were each scored with this signature. Kaplan-Meier curve compares distant metastasis-free survival in BC patients with relatively higher signature scoring versus those with lower scoring. Patient data were extracted from publicly available datasets using http://kmplot.com/.