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. 2019 Nov 13;8(11):1954. doi: 10.3390/jcm8111954

Figure 2.

Figure 2

Figure 2

Figure 2

Increased nuclear staining of NFκB in recurrent bladder tumor tissue compared with pre-treatment tumor tissue is shown in a patient with T3N0M0 bladder cancer treated with trimodality bladder-preserving therapy and developing (A) local bladder recurrence, (B) inguinal node metastasis, and (C) mediastinal node metastasis on computed tomography at 7 months, 22 months, and 29 months, respectively. (D) Immunohistochemical staining of NFκB and p16 in pre-treatment and recurrent bladder tumors at magnifications of 200× (scale bar: 100 μm).