Table 1.
Patient characteristics (n = 1125).
| Characteristics | Total n = 1125 (%) |
Pre-Menopausal n = 209 (%) |
Post-Menopausal n = 916 (%) |
|---|---|---|---|
| Median age, years (range) | 61 (26–88) | 46 (26–63) | 64 (31–88) |
| Daily dietary calcium intake | |||
| ≥RDA | 824 | 140 (67.0) | 684 (74.7) |
| <RDA | 301 | 69 (33.0) | 232 (25.3) |
| Normal alcohol consumption | |||
| Yes | 198 | 26 (13.8) | 172 (20.5) |
| No | 828 | 162 (86.2) | 666 (79.5) |
| Missing | 99 | 21 | 78 |
| Normal physical activity | |||
| Yes | 732 | 139 (67.5) | 593 (65.2) |
| No | 384 | 67 (32.5) | 317 (34.8) |
| Missing | 9 | 3 | 6 |
| Smoking habits | |||
| Current or former smoker | 223 | 44 (21.3) | 179 (19.7) |
| Never smoker | 893 | 163 (78.7) | 730 (80.3) |
| Missing | 9 | 2 | 7 |
| Back pain | |||
| Yes | 594 | 98 (47.3) | 496 (55.2) |
| No | 511 | 109 (52.7) | 402 (44.8) |
| Missing | 20 | 2 | 18 |
| Bisphosphonate therapy | |||
| Yes | 156 | 12 (94.0) | 144 (16.3) |
| No | 932 | 190 (6.0) | 742 (83.7) |
| Missing | 37 | 7 | 30 |
| Body Mass Index (BMI) | |||
| <25 | 569 | 141 (67.8) | 428 (47.0) |
| 25–29 | 381 | 51 (24.5) | 330 (36.3) |
| ≥30 | 168 | 16 (7.7) | 152 (16.7) |
| Missing | 7 | 1 | 6 |
| CTX < 0.6 | 447 | 84 (64.6) | 363 (63.4) |
| CTX ≥ 0.6 | 256 | 46 (35.4) | 210 (36.6) |
| Missing | 422 | 79 | 343 |
| BMD measurement | |||
| Spine DXA scan | 435 | 109 (56.5) | 326 (38.0) |
| Hip DXA scan | 272 | 3 (1.6) | 269 (31.4) |
| Qus | 339 | 79 (40.9) | 260 (30.6) |
| X-rays | |||
| Cervical | 36 | 6 (2.9) | 30 (3.3) |
| Lumbar | 455 | 82 (39.2) | 373 (40.7) |
| Dorsal | 668 | 115 (54.9) | 553 (60.4) |
| Not specified | 6 | 6 | - |
| Bone mineral density (BMD) | |||
| T score ≤ −2.5 | 333 | 38 (19.7) | 295 (34.4) |
| T score > −2.5 and ≤ −1.0 | 500 | 90 (46.6) | 410 (47.8) |
| T score > −1.0 | 217 | 65 (33.7) | 152 (17.7) |
| Missing | 75 | 16 | 59 |
| Endocrine therapy | |||
| AI + AI + TAM | 780 | - | 780 (85.2) |
| TAM | 136 | - | 136 (14.8) |
| LHRH + AI and LHRH alone | 87 | 87 (41.6) | - |
| Other | 122 | 122 (58.4) | - |
| Vitamin D level (ng/mL) | |||
| ≤10 | 192 | 19 (9.5) | 173 (19.9) |
| >10 | 875 | 180 (90.5) | 695 (80.1) |
| PTH | |||
| Normal | 838 | 169 (92.3) | 669 (85.1) |
| Abnormal | 131 | 14 (7.7) | 117 (14.9) |
| Missing | 156 | 26 | 130 |
| pT | |||
| T0–T1 | 779 | 145 (75.5) | 634 (75.5) |
| T2–T3 | 253 | 47 (24.5) | 206 (24.5) |
| Missing | 96 | 17 | 76 |
| pN | |||
| N0 | 648 | 113 (61.7) | 535 (69.0) |
| N1 | 310 | 70 (38.3) | 240 (31.0) |
| Missing | 165 | 26 | 139 |
RDA: Recommended Daily Allowance; CTX: Carboxy-terminal telopeptide of type I collagen; AI: Aromatase inhibitor; TAM: Tamoxifen; LHRH: Luteinizing hormone-releasing hormone; pT: Primary tumor; pN: Regional lymph nodes; PTH: Parathyroid hormone.