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. 2019 Nov 14;8(11):1439. doi: 10.3390/cells8111439

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of EAE sub-immunization on gait parameters. (A) Differences of the gait metrics in Control^DigiGait, PTx^DigiGait, and EAE^DigiGait mice. D’Agostino and Pearson test was applied to test for normal distribution of the data. p-values generated using one-way ANOVA with Bonferroni post-test for multiple comparisons of individual pairs of treatment. Note that the gait parameter Swing Time is significantly different between sub-immunized (PTx^DigiGait) and fully immunized (EAE^DigiGait) mice. (B) Gait parameters over time in fully immunized (EAE^DigiGait) mice. Don = day of onset, Don-1 = 1 day before onset, etc. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, ns = not significant.