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. 2019 Oct 31;8(11):1365. doi: 10.3390/cells8111365

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cellular origin and expression profiles of transcriptional factors in different B-cell lymphomas. Schematic representation of the cellular origins of different subtypes of B-cell lymphomas: Burkitt lymphoma (BL) is reported to originate from centroblasts from the dark zone (DZ); germinal centre B cell-like (GCB)-diffuse large B cell lymphoma (DLBL) and follicular lymphoma (FL) have features resembling cells from the light zone (LZ); and activated B cell-like (ABC)- DLBCL is related to B-cell terminal differentiation before the plasma cell stage. The names of overexpressed genes are indicated in red, and the names of downregulated genes are indicated in blue. * genes reported to be deregulated in t-FL.