Table 4.

Estimated effect in terms of the absolute numbers of event reductions and their associated direct costs for different supplementation regimes in the general population, projected in 2025. The median and the 95% credibility interval are reported. Reported events are expressed in millions of events (95% C.I. lower bound; median; 95% C.I. upper bound), while direct costs are expressed in billions of dollars (95% C.I. lower bound; median; 95% C.I. upper bound).

		Coronary Heart Disease		Stroke		Heart Failure
		Events	Direct Costs	Events	Direct Costs	Events	Direct Costs
Encapsulated fruit and vegetable	TC	(29.97, 36.26, 53.72)	(52.16, 63.65, 100.01)	(1.26, 1.98, 4.76)	(4.42, 6.91, 17.26)
	LDL	(0.17, 0.61, 1.9)	(0.29, 1.07, 3.44)
	HCY	(55.7, 62.41, 81.12)	(96.17, 109.76, 153.44)
	SBP	(6.47, 8.87, 16.17)	(11.34, 15.54, 29.6)	(4.38, 6.02, 10.66)	(15.13, 21.07, 39.03)	(0.45, 0.71, 1.82)	(1.56, 2.49, 6.7)
	TNF-α	(1.17, 1.85, 3.67)	(2.05, 3.23, 6.7)	(10.34, 11.21, 13.5)	(35.21, 39.14, 52.25)
Orange juice	TC	(7.04, 21.08, 42.86)	(12.37, 37.11, 78.92)	(0.26, 1.24, 5.8)
	LDL	(−0.77, 4.9, 20.7)	(−1.36, 8.69, 37.37)	(0.93, 4.36, 20.82)
Fruit and vegetable drink	TC	(4.86, 11.54, 28.72)	(8.43, 20.31, 52.57)	(0.19, 0.65, 2.88)	(0.67, 2.26, 10.38)
	LDL	(−0.35, 2.32, 10.2)	(−0.63, 4.06, 18.37)
	HCY	(−1.35, 1.47, 9.4)	(−2.4, 2.55, 17.02)
	SBP	(−5.89, 2.33, 24.57)	(−10.29, 4.15, 44.62)	(−4.04, 1.58, 16.05)	(−14.24, 5.54, 57.98)	(−0.47, 0.16, 2.47)	(−1.63, 0.57, 8.86)
	BMI					(−0.48, 0.32, 2.6)	(−1.7, 1.11, 9.37)
Cherry juice	TC	(13.76, 21.01, 37.24)	(24.34, 36.8, 69.27)	(0.66, 1.33, 4.26)	(2.31, 4.69, 15.32)
	SBP	(2.87, 11.88, 35.46)	(5.05, 20.71, 64.77)	(1.97, 7.94, 22.95)	(6.8, 27.7, 82.37)	(0.67, 3.01, 13.8)	(1.97, 7.94, 22.95)
Fruit juice	TC	(−7.46, 8.62, 46.75)	(−13.07, 15, 84.05)	(−0.3, 0.33, 3.37)	(−1.04, 1.15, 12.05)
	LDL	(−1.71, 2.66, 15.16)	(−3.05, 4.65, 27.24)