Table 6.
Estimated effect in terms of the absolute number of event reductions and their associated direct costs for different supplementation regimes in subjects with metabolic syndrome, projected in 2025. The median and the 95% credibility interval are reported. Reported events are expressed in millions of events (95% C.I. lower bound; median; 95% C.I. upper bound), while direct costs are expressed in billions of dollars (95% C.I. lower bound; median; 95% C.I. upper bound).
| Coronary Heart Disease | Stroke | Heart Failure | |||||
|---|---|---|---|---|---|---|---|
| Events | Direct Costs | Events | Direct Costs | Events | Direct Costs | ||
| Encapsulated fruit and vegetable | TC | (−0.98, 2.75, 13.15) | (−1.72, 4.81, 23.95) | (−0.03, 0.09, 0.86) | (−0.11, 0.31, 3.05) | ||
| LDL | (−0.42, −0.15, 0.63) | (−0.74, −0.26, 1.12) | |||||
| HCY | (0.63, 0.74, 1.17) | (1.1, 1.32, 2.17) | |||||
| SBP | (4.53, 6.37, 12.56) | (7.94, 11.26, 22.98) | (2.94, 4.22, 8.81) | (10.29, 14.86, 31.86) | (0.96, 1.43, 3.29) | (3.32, 4.97, 12.12) | |
| TNF-α | (1.94, 3.15, 6.75) | (3.39, 5.51, 12.29) | (1.34, 1.83, 2.57) | (4.68, 6.35, 9.83) | |||
| Artichoke leaf juice | TC | (−11.85, 4.78, 43.02) | (−20.92, 8.47, 77) | (−0.44, 0.13, 3.34) | (−1.55, 0.45, 11.75) | ||
| LDL | (−8.42, 3.86, 36.24) | (−14.77, 6.79, 65.79) | |||||
| Orange juice | TC | (18.34, 29.12, 57.4) | (32.14, 51.27, 104.71) | (0.58, 1.35, 5.38) | (2.03, 4.75, 19.43) | ||
| LDL | (13.5, 22.47, 49.67) | (23.7, 39.79, 90.37) | |||||
| Fruit and vegetable drink | TC | (3.77, 9.51, 26.52) | (6.62, 16.69, 48.85) | (0.09, 0.37, 1.97) | (0.31, 1.31, 7.15) | ||
| LDL | (−0.64, 3.95, 17.75) | (−1.1, 6.89, 31.88) | |||||
| HCY | (−0.93, 1.08, 7.02) | (−1.64, 1.9, 12.63) | |||||
| SBP | (−4.33, 1.68, 18.67) | (−7.7, 2.95, 33.56) | (−2.97, 1.13, 12.52) | (−10.42, 3.94, 44.67) | (−0.98, 0.38, 4.62) | (−3.44, 1.32, 16.85) | |
| BMI | (−0.6, 0.43, 3.44) | (−2.09, 1.47, 12.09) | |||||
| Cherry juice | TC | (11.2, 17.7, 37.3) | (19.6, 31.01, 68.63) | (0.35, 0.79, 3.03) | (1.23, 2.77, 10.86) | ||
| SBP | (2.11, 8.46, 27.36) | (3.73, 14.85, 49.34) | (1.39, 5.56, 18.25) | (4.77, 19.37, 65.62) | (0.47, 1.84, 6.81) | (1.63, 6.44, 24.69) | |
| Fruit juice | TC | (−4.71, 6.31, 34.51) | (−8.34, 11.02, 62.33) | (−0.17, 0.19, 2.4) | (−0.58, 0.66, 8.6) | ||
| LDL | (−3.05, 4.18, 25.21) | (−5.3, 7.41, 46.22) | |||||