Abbreviation	Description
ABI	aggregation-prone inhibition
BBR	base-binding region
BSA	bovine serum albumin
CAC	critical aggregation concentration
cAMP	cyclic adenosine monophosphate
CBD	cAMP binding domain
CD25HD	classic CD25 homology domain
CHESPA	chemical shift projection analyses
CMC	critical micellar concentration
CNG	cyclic nucleotide gated channels
CR	catalytic region
DLS	dynamic light scattering
EPAC	exchange protein directly activated by cAMP
ESI	EPAC-specific inhibitor
GTP	guanosine triphosphate
GDP	guanosine diphosphate
HCN	hyperpolarization activated cyclic nucleotide gated channels
HSA	human serum albumin
HSQC	heteronuclear single quantum coherence
HTS	high-throughput screen
IL	ionic latch
Kd	dissociation constant
PBC	phosphate-binding cassette
PKA	cAMP-dependent protein kinase A
Popdc	Popeye domain containing proteins
PRE	paramagnetic relaxation enhancement
RA	Ras association domain
REM	Ras-exchange motif
RR	regulatory region
SLAPSTIC	spin-labels attached to protein side chain
SPR	surface plasmon resonance
STD	saturation transfer difference
TEM	transmission electron microscopy
TX	Triton X100